The cerebrospinal fluid (CSF) is the serum-like
fluid that flows within the brain. It
is clear, colorless liquid that circulates
around the brain and the spinal cord.
CSF protects the brain and the spinal
cord by providing a safety cushion against
shocks and injuries.
The CSF is manufactured by the
choroid plexus, a string of infolded blood
vessels opening into the cerebral ventricles.
CSF gets absorbed into the venous system.
If the rate of production of CSF
is more than its absorption, the CSF pressure
mounts and results in hydrocephalus, a
potentially deadly situation. CSF may
also accumulate if the CSF course is blocked
somwehere within the system.
The CSF test is recommended for
the diagnosis of a various neurological
diseases. It is performed to estimate
the number of red and white blood cells
in the cerebrospinal fluid. Presence
of red blood cells, may suggest a hemorrhage.
CSF is also analyzed for levels of glucose
and protein within it, abnormalities in
these, may help differentiate the cause
of meningitis, bacterial vs, viral, for
example.
Procedure
called lumbar puncture is carried out
to obtain the CSF from the body.
The CSF cell count helps diagnose
and follow up various disorders, such
as meningitis and other diseases of the
brain or the spinal cord. It also helps
diagnose a tumor, or inflammation.
A rise in white blood cells suggests
infection, inflammation or hemorrhage
into the cerebrospinal fluid. This may
occur due to meningitis, encephalitis,
severe infection, tumor, abscess , and
bleeding.
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