Hemoglobin
is the iron-containing metalloprotein,
which assists in the transport of oxygen
in blood through Red
Blood Cells (RBCs).
Hemoglobin transports oxygen from lungs
to the rest of the body. The mutation
of genes in the hemoglobin protein can
cause several hereditary diseases, such
as sickle-cell anemia and thalassemia.
Hemoglobin test
is used to measure the amount of hemoglobin.
It indicates how well our blood can carry
oxygen throughout the body. It also helps
in determining the severity of anemia
in which body contains very few RBCs
or polycythemia in which, the body has
a large number of RBCs.
The test helps in monitoring the treatment
of anemia and polycythemia. It also enables
the doctor to decide whether the body
requires blood transfusion during the
treatment of anemia. Hemoglobin test can
also be a part of Complete Blood Count
(CBC). Patients suffering from continuous
bleeding problems are also recommended
to get their hemoglobin tested.
The blood of
an adult should normally contain 12 to
18 grams of hemoglobin per deciliter.
The hemoglobin level can elevate above
normal due to dehydration, excess manufacturing
of RBCs
in the bone marrow, and severe lung disease.
The low hemoglobin level causes anemia,
which may be due to the deficiency of
iron and other essential vitamins, such
as B6, B12, and folate. It can also be
a genetic defect as in sickle-cell anemia
or may be caused by liver cirrhosis, kidney
diseases, and excessive bleedings to name
a few.
Hemoglobin test
should also be done during pregnancy to
check if the count is normal or has decreased.
Study shows that hemoglobin level rises
around eight in the morning and decreases
around 8 in the evening. People who smoke
heavily and those who stay on high altitudes
have higher count of RBCs.
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